Description

Fosravuconazole Bis(L-Lysine) is a lysine salt derivative of the potent triazole antifungal agent, fosravuconazole, designed to enhance solubility and bioavailability. This compound is critical for the development of advanced pharmaceutical formulations, particularly for systemic antifungal therapies. It serves as a key pharmaceutical intermediate for researchers and manufacturers in the agrochemical and pharmaceutical industries seeking to develop more effective and stable antifungal products.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of advanced antifungal APIs (Active Pharmaceutical Ingredients).
• Agrochemical Research: Development of novel systemic fungicides for crop protection.
• Veterinary Medicine: Formulation research for antifungal treatments in animals.
• Clinical Research: Investigational new drug (IND) development for treating systemic fungal infections.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing.
• Solubility Enhancement Studies: Used in pre-formulation research to improve drug delivery profiles.

Basic Information

Item	Detail
Product Name	Fosravuconazole Bis(L-Lysine)
CAS No.	1035654-66-0
Molecular Formula	C26H46FN7O8
Molecular Weight	603.70 g/mol
Synonyms	Fosravuconazole L-Lysine Salt; Fosravuconazole Lysinate; (2R,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoro-4-(4-(pent-4-yn-1-yl)phenyl)pyrimidin-2-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol bis(L-lysinate) phosphate; BFE 1225 Lysine Salt; E 1225 Lysine Salt; Fosravuconazole Dilisinate; Antifungal Agent E1225 Lysine Salt
EINECS	Contact for details

Quality Control

Our Fosravuconazole Bis(L-Lysine) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.