Description

Tak-733 is a potent and selective small molecule inhibitor with significant research and development applications. This high-purity compound is essential for advancing studies in targeted therapeutic areas, offering researchers a reliable tool for biochemical and pharmacological investigation. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in drug discovery and mechanism of action studies.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in preclinical drug discovery programs.
• Biochemical Assays: Used as a selective inhibitor in enzymatic and cellular assays to study specific biological pathways and validate drug targets.
• Academic Research: Employed in university and institutional labs for fundamental research into disease mechanisms and cellular signaling.
• Preclinical Studies: Utilized in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and toxicology profiles.
• Chemical Probe Development: Acts as a starting point or comparator in the design and synthesis of novel chemical probes for target validation.

Basic Information

Product Name	Tak-733
CAS No.	1035555-63-5
Molecular Formula	C₂₃H₂₅FN₄O₃
Molecular Weight	424.47 g/mol
Synonyms	TAK-733; TAK 733; 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine; MEK Inhibitor TAK-733; (R)-6-(4-((4-ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; TAK733; GDC-0973 analog
EINECS	Contact for details

Quality Control

Our Tak-733 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee product integrity and support your research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.