Description

4-Ethoxy-2-Fluorobenzoyl Chloride, 97% is a high-purity, functionalized benzoyl chloride derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of an ethoxy group and a fluorine atom on the aromatic ring, enabling precise structural modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for creating active ingredients and fine chemicals that require specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification Agent: Employed to introduce fluorinated benzoyl groups into polymer chains, altering material properties like solubility and thermal stability.
• Peptide Coupling Reagent Derivative: Can be utilized to activate carboxylic acids in peptide synthesis and other amide bond formation reactions.
• Research & Development: A valuable tool for medicinal chemistry and material science research exploring structure-activity relationships (SAR).

Basic Information

Product Name	4-Ethoxy-2-Fluorobenzoyl Chloride, 97%
CAS No.	1034248-85-5
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	2-Fluoro-4-ethoxybenzoyl chloride; 4-Ethoxy-2-fluorobenzoic acid chloride; 2-Fluoro-4-ethoxybenzoic acid chloride; 4-Ethoxy-2-fluorobenzoyl chloride; 1034248-85-5; 2-Fluoro-4-ethoxy-benzoyl chloride; p-Ethoxy-o-fluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2-Fluorobenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and assay. A Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with water and alcohols; ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and purity. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.