Description

1-(4-Bromo-2-Fluorophenyl)-2,2,2-Trifluoroethanol is a high-value fluorinated aromatic building block, distinguished by its unique combination of bromo, fluoro, and trifluoroethanol functional groups. This compound is critical for advanced organic synthesis, offering versatile reactivity for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of next-generation herbicides and fungicides, leveraging the stability and bioactivity imparted by its fluorine atoms.
• Liquid Crystal Material Development: Used in the synthesis of fluorinated components for advanced liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: The bromine atom provides a handle for cross-coupling reactions (e.g., Suzuki, Negishi), while the alcohol group allows for further functionalization, making it a versatile scaffold.
• Material Science Research: Employed in the development of novel polymers and coatings with enhanced chemical resistance and specific surface properties.

Basic Information

Product Name	1-(4-Bromo-2-Fluorophenyl)-2,2,2-Trifluoroethanol
CAS No.	1033805-88-7
Molecular Formula	C8H5BrF4O
Molecular Weight	273.03 g/mol
Synonyms	4-Bromo-2-fluoro-α-(trifluoromethyl)benzyl alcohol; (4-Bromo-2-fluorophenyl)(trifluoromethyl)methanol; 2,2,2-Trifluoro-1-(4-bromo-2-fluorophenyl)ethanol; 1-(4-Bromo-2-fluorophenyl)-2,2,2-trifluoroethan-1-ol; α-(Trifluoromethyl)-4-bromo-2-fluorobenzyl alcohol; 4-Bromo-2-fluoro-α,α,α-trifluorotoluene-α-ol
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromo-2-Fluorophenyl)-2,2,2-Trifluoroethanol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.