Description

Cyclohexaneacetic Acid, 4-[4-(Chlorocarbonyl)Phenyl]-, Ethyl Ester, trans- is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific trans configuration and reactive carbonyl groups are essential. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and fine chemical industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, particularly those targeting specific biological pathways.
• Prostaglandin Analog Synthesis: Serves as a crucial building block for the development of prostaglandin and prostacyclin receptor agonists.
• Chemical Research & Development: Used in academic and industrial labs for exploring new synthetic routes and creating novel chemical entities for biological screening.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals requiring precise structural control.
• Liquid Crystal Material Synthesis: Potential use in the creation of advanced organic materials due to its rigid, substituted aromatic and cyclohexyl structure.

Basic Information

Item	Detail
Product Name	Cyclohexaneacetic Acid, 4-[4-(Chlorocarbonyl)Phenyl]-, Ethyl Ester, trans-
CAS No.	1031336-68-1
Molecular Formula	C17H19ClO4
Molecular Weight	322.78 g/mol
Synonyms	trans-4-[4-(Chlorocarbonyl)phenyl]cyclohexaneacetic acid ethyl ester; Ethyl (1r,4r)-4-[4-(chlorocarbonyl)phenyl]cyclohexaneacetate; UNII-7J2S5I22K5; 7J2S5I22K5; Ethyl 4-[4-(chloroformyl)phenyl]cyclohexylacetate, trans-; AURORA KA-4331; trans-Ethyl 4-(4-(chlorocarbonyl)phenyl)cyclohexaneacetate; (1r,4r)-Ethyl 4-(4-(chlorocarbonyl)phenyl)cyclohexaneacetate
EINECS	Contact for details

Quality Control

Our Cyclohexaneacetic Acid, 4-[4-(Chlorocarbonyl)Phenyl]-, Ethyl Ester, trans- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with ICH guidelines for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.