Description

Plx-4032 (Rg7024) is a high-purity, small-molecule chemical compound with the CAS registry number 1029872-54-5. This compound is of significant interest in advanced research and development, particularly for its role as a selective kinase inhibitor. It is primarily sought after by pharmaceutical R&D teams, biotechnology firms, and academic research institutions engaged in oncology and targeted therapy development. Our supply ensures consistent quality and reliable availability for critical research applications.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of targeted cancer therapies.
• Biochemical Assays: Used as a selective inhibitor in kinase profiling and enzymatic studies to understand signaling pathways.
• Preclinical Studies: Employed in in vitro and in vivo models to investigate efficacy, pharmacokinetics, and mechanism of action.
• Chemical Biology: A valuable tool compound for probing protein function and validating drug targets in cellular systems.
• Standards & Metrology: Supplied as a certified reference material for analytical method development and quality control in laboratories.

Basic Information

Product Name	Plx-4032 (Rg7024)
CAS No.	1029872-54-5
Molecular Formula	C23H18F3N5O3S
Molecular Weight	501.48 g/mol
Synonyms	Vemurafenib; PLX4032; RG7204; RO5185426; 1H-Pyrrole-2,5-dione, 3-[4-[4-[[2-[(2-chloro-4-pyridinyl)amino]-5-fluorophenyl]amino]-5-fluoro-2-pyrimidinyl]amino]phenyl]-; 5-Fluoro-3-phenyl-2-[(S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone; BRAF V600E inhibitor
EINECS	Contact for details

Quality Control

Our Plx-4032 (Rg7024) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports your need for reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.