Description

Mln-8237 is a high-purity, non-commercial chemical compound identified by CAS NO 1028486-01-2, primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its value lies in enabling the synthesis of novel therapeutic agents, particularly in targeted oncology and kinase inhibitor pathways. This product is essential for research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the discovery and development of next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Research: Used in the development and optimization of potent and selective kinase inhibitors for cancer therapy.
• Preclinical Studies: Serves as a reference standard or starting material for in vitro and in vivo pharmacological testing.
• Process Chemistry & Scale-Up: Employed in route scouting and process optimization for efficient and scalable API manufacturing.
• Chemical Biology Probes: Utilized to create tool compounds for studying specific biological pathways and target validation.

Basic Information

Product Name	Mln-8237
CAS No.	1028486-01-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MLN8237; Alisertib; (S)-Alisertib; Aurora A Kinase Inhibitor MLN8237; 4-[[(9S)-7-Methyl-6-oxo-8,9,10,11-tetrahydro-7H-azepino[4,5-b]thieno[2,3-d]pyridin-9-yl]amino]benzoic acid; Benzoic acid, 4-[[(9S)-7-methyl-6-oxo-8,9,10,11-tetrahydro-7H-azepino[4,5-b]thieno[2,3-d]pyridin-9-yl]amino]-; UNII-8C6Y0P5V8P
EINECS	Contact for details

Quality Control

Every batch of Mln-8237 (Alisertib) is produced and tested under strict quality management systems to ensure identity, purity, and consistency suitable for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.