Description

Bez235 (Tosylate) CAS NO 1028385-32-1 is a high-purity chemical intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of novel therapeutic agents, particularly in targeted oncology and other specialized medicinal chemistry applications. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of new molecular entities.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Oncology Research: Used as a building block for novel kinase inhibitors and other targeted cancer therapies under investigation.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry Development: Serves as a reference standard and starting material for scaling up synthetic routes in pilot plants.
• Biochemical Research: Utilized as a tool compound in enzymatic and cellular assay development for target validation.
• Custom Synthesis: Basis for the preparation of labeled analogs (e.g., deuterated, C13) for metabolic and pharmacokinetic studies.

Basic Information

Product Name	Bez235 (Tosylate)
CAS No.	1028385-32-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NVP-BEZ235 tosylate; BEZ 235 Tosylate Salt; Dactolisib Tosylate; BEZ-235 (Tosylate); (Tosyloxy)-BEZ235; PI3K/mTOR Inhibitor BEZ235 Tosylate; 2-Methyl-2-[4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl]propanenitrile 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our Bez235 (Tosylate) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.