Description

2,4-Difluorobenzylisothiocyanate is a versatile and reactive organofluorine building block, specifically an isothiocyanate derivative. This compound is valued for its role as a key synthetic intermediate in the development of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the difluorobenzyl and isothiocyanate moieties can impart specific biological properties.
• Chemical Biology Probe Development: Acts as a reactive handle for bioconjugation, enabling the creation of probes to study protein function and interactions.
• Material Science Research: Employed in the synthesis of specialized polymers or organic materials where fluorine incorporation is desired for stability or unique electronic properties.
• Ligand and Catalyst Preparation: Useful for constructing novel ligands or organocatalysts used in asymmetric synthesis and other advanced chemical transformations.

Basic Information

Product Name	2,4-Difluorobenzylisothiocyanate
CAS No.	1027513-62-7
Molecular Formula	C8H5F2NS
Molecular Weight	185.20 g/mol
Synonyms	2,4-Difluorobenzyl Isothiocyanate; 1-(Isothiocyanatomethyl)-2,4-difluorobenzene; (2,4-Difluorophenyl)methyl Isothiocyanate; 2,4-Difluoro-α-isothiocyanatotoluene; Benzene, 1-(isothiocyanatomethyl)-2,4-difluoro-; 2,4-Difluorobenzyl mustard oil
EINECS	Contact for details

Quality Control

Our 2,4-Difluorobenzylisothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.