Description

4-Bromo-5-Fluoro-2-Methylphenylisothiocyanate is a high-purity, synthetically valuable aromatic isothiocyanate derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the introduction of a reactive isothiocyanate functional group into complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel agrochemicals, pharmaceuticals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in creating novel herbicides, fungicides, or insecticides by serving as a core scaffold for bioactive molecule development.
• Chemical Biology Probe Synthesis: Employed to create isothiocyanate-functionalized probes for labeling proteins or studying biological pathways.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialized polymers with unique thermal or chemical resistance properties.
• Organic Synthesis Building Block: Provides a versatile handle for further chemical transformations, including cyclization reactions to form heterocyclic compounds like benzothiazoles.

Basic Information

Product Name	4-Bromo-5-Fluoro-2-Methylphenylisothiocyanate
CAS No.	1027512-16-8
Molecular Formula	C8H5BrFNS
Molecular Weight	246.10 g/mol
Synonyms	2-Methyl-4-bromo-5-fluorophenyl isothiocyanate; 4-Bromo-5-fluoro-o-tolyl isothiocyanate; 1-Bromo-2-fluoro-4-isothiocyanato-5-methylbenzene; (4-Bromo-5-fluoro-2-methylphenyl) isothiocyanate; Isothiocyanic acid, 4-bromo-5-fluoro-2-methylphenyl ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Fluoro-2-Methylphenylisothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.