Description

(1S)-1-(4-Bromo-2-Fluorophenyl)Ethan-1-Ol is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key building block for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. This compound is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel, stereochemically defined therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds for drug discovery and development.
• Organic Synthesis Research: Serves as a versatile reagent in academic and industrial R&D for constructing fluorinated and brominated aromatic systems.
• Ligand and Catalyst Development: Potential precursor for chiral ligands used in catalytic asymmetric transformations.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(1S)-1-(4-Bromo-2-Fluorophenyl)Ethan-1-Ol
CAS No.	1026088-11-8
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	(S)-1-(4-Bromo-2-fluorophenyl)ethanol; (1S)-1-(4-Bromo-2-fluorophenyl)ethanol; (S)-4-Bromo-2-fluoro-α-methylbenzyl alcohol; (S)-α-Methyl-4-bromo-2-fluorobenzyl alcohol; (S)-1-(4-Bromo-2-fluoro-phenyl)-ethanol; (S)-(-)-1-(4-Bromo-2-fluorophenyl)ethanol; (1S)-(-)-1-(4-Bromo-2-fluorophenyl)ethanol; (S)-1-(4-Bromo-2-fluorophenyl)ethyl alcohol
EINECS	Contact for details

Quality Control

Our (1S)-1-(4-Bromo-2-Fluorophenyl)Ethan-1-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity and chemical purity, verified by advanced chromatographic techniques. A Certificate of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.