Description

1-[(2-Fluoro-4-Phenylsulfonyl)Phenyl]-Homopiperazine is a specialized fluorinated and sulfonated heterocyclic compound that serves as a high-value pharmaceutical intermediate and research chemical. Its unique molecular architecture, featuring a homopiperazine core linked to a fluorinated phenylsulfonyl moiety, makes it a critical building block for the synthesis of novel bioactive molecules. This compound is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring targeted molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Synthesis: The sulfonyl and fluorinated aromatic groups are characteristic of scaffolds used in developing enzyme inhibitors.
• Ligand for Receptor Studies: Potential use in creating ligands for pharmacological profiling and receptor binding assays.
• Advanced Material Precursor: May serve as a monomer or functional additive in the development of specialty polymers with specific electronic or surface properties.

Basic Information

Product Name	1-[(2-Fluoro-4-Phenylsulfonyl)Phenyl]-Homopiperazine
CAS No.	1020722-23-9
Molecular Formula	C17H17FN2O2S
Molecular Weight	332.39 g/mol
Synonyms	1-[(2-Fluoro-4-(phenylsulfonyl)phenyl]homopiperazine; 1-(2-Fluoro-4-(phenylsulfonyl)phenyl)hexahydro-1H-1,4-diazepine; 1-(2-Fluoro-4-(benzenesulfonyl)phenyl)homopiperazine; 1,4-Diazepine, 1-[2-fluoro-4-(phenylsulfonyl)phenyl]hexahydro-; Homopiperazine, 1-[2-fluoro-4-(phenylsulfonyl)phenyl]-; 1020722-23-9 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 1-[(2-Fluoro-4-Phenylsulfonyl)Phenyl]-Homopiperazine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or manufacturing specifications. Our commitment is to deliver material of consistent high purity and reliable performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should be conducted under controlled lighting conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.