Description

2-Bromo-6-Fluorobenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile halogenated benzoyl moiety for introducing specific functional groups into target molecules, enabling precise structural modifications. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the bromo-fluoro substitution pattern confers specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of novel polymers and liquid crystals with tailored electronic and optical properties.
• Peptide Modification: Useful as an acylating agent for modifying peptides or introducing fluorinated tags for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-6-Fluorobenzoyl Chloride
CAS No.	1020718-20-0
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	2-Bromo-6-fluorobenzoic acid chloride; 6-Fluoro-2-bromobenzoyl chloride; (2-Bromo-6-fluorophenyl)(chloro)methanone; 2-Bromo-6-fluorobenzenecarbonyl chloride; o-Bromo-o-fluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.