Description

Ert-Butyl 4-(Bromomethylene)Piperidine-1-Carboxylate is a high-value, advanced pharmaceutical intermediate characterized by its reactive bromomethylene and protected piperidine structure. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of complex molecules for drug discovery and development. It is primarily needed by research institutions and pharmaceutical companies engaged in creating novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Alkaloid Analog Synthesis: Serves as a precursor for constructing complex piperidine-based alkaloid analogs and heterocyclic compounds.
• Ligand and Probe Development: Employed in the creation of specialized chemical probes and ligands for biological target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom fine chemicals.

Basic Information

Product Name	Ert-Butyl 4-(Bromomethylene)Piperidine-1-Carboxylate
CAS No.	1020329-80-9
Molecular Formula	C12H20BrNO2
Molecular Weight	290.20 g/mol
Synonyms	tert-Butyl 4-(bromomethylene)piperidine-1-carboxylate; 1-Boc-4-(bromomethylene)piperidine; 4-(Bromomethylene)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(bromomethylene)piperidine; N-Boc-4-(bromomethylene)piperidine; 4-Bromomethylene-1-N-Boc-piperidine; Piperidine-1-carboxylic acid, 4-(bromomethylene)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Ert-Butyl 4-(Bromomethylene)Piperidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and degradation. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.