Description

n-[3-tert-Butyl-1-(Quinolin-6-Yl)-1H-Pyrazol-5-Yl]-N'-[2-Fluoro-4-[(2-(Methylcarbamoyl)Pyridin-4-Yl)Oxy]Phenyl]Urea is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of targeted therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a precise molecular scaffold for creating novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing innovative small-molecule therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for targeted therapies.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitor candidates due to its specific heterocyclic structure.
• Oncology Drug Discovery: A crucial precursor in research programs aimed at discovering new anti-cancer agents.
• Medicinal Chemistry: Employed for structure-activity relationship (SAR) studies and lead optimization in drug discovery pipelines.
• Biochemical Research: Used as a reference standard or probe in biochemical assays to study specific biological pathways.
• Custom Synthesis: Supplied to contract research organizations (CROs) and CDMOs for custom synthesis and scale-up projects.

Basic Information

Product Name	n-[3-tert-Butyl-1-(Quinolin-6-Yl)-1H-Pyrazol-5-Yl]-N'-[2-Fluoro-4-[(2-(Methylcarbamoyl)Pyridin-4-Yl)Oxy]Phenyl]Urea
CAS No.	1020172-07-9
Molecular Formula	C31H30FN7O4
Molecular Weight	583.62 g/mol
Synonyms	1020172-07-9; UNII-9FQ6S1B8V5; 9FQ6S1B8V5; N-[3-(tert-Butyl)-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[[2-(methylcarbamoyl)pyridin-4-yl]oxy]phenyl]urea; BMS-794833; BMS794833; BMS 794833
EINECS	Contact for details

Quality Control

Our production of n-[3-tert-Butyl-1-(Quinolin-6-Yl)-1H-Pyrazol-5-Yl]-N'-[2-Fluoro-4-[(2-(Methylcarbamoyl)Pyridin-4-Yl)Oxy]Phenyl]Urea adheres to stringent quality management systems, ensuring batch-to-batch consistency suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.