Description

tert-Butyl4-(5-Chloro-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate is a high-value, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for oncology and antiviral drug candidates.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing novel kinase inhibitors due to its pyrrolopyridine-piperazine motif.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Biochemical Tool Compound: Employed in biochemical assays and high-throughput screening to identify and validate new biological targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	tert-Butyl4-(5-Chloro-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate
CAS No.	1020056-91-0
Molecular Formula	C16H21ClN4O2
Molecular Weight	336.82 g/mol
Synonyms	tert-Butyl 4-(5-chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine-1-carboxylate; 1-Boc-4-(5-chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine; 4-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine-1-carboxylic acid tert-butyl ester; 1020056-91-0; 5-Chloro-4-(1-piperazinyl)-1H-pyrrolo[2,3-b]pyridine 1-Boc derivative; N-Boc-4-(5-chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl4-(5-Chloro-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.