Description

2-(Trifluoromethyl)Isonicotinoyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in the trifluoromethyl and acid chloride functional groups, which enable efficient derivatization to create novel compounds with enhanced properties. This product is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing active ingredients and exploring new molecular entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and other advanced materials requiring specific electronic properties.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for studying biological systems and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(Trifluoromethyl)Isonicotinoyl Chloride
CAS No.	1019201-53-6
Molecular Formula	C7H3ClF3NO
Molecular Weight	209.55 g/mol
Synonyms	2-(Trifluoromethyl)pyridine-4-carbonyl chloride; 4-Pyridinecarbonyl chloride, 2-(trifluoromethyl)-; Isonicotinoyl chloride, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)isonicotinic acid chloride; 2-Trifluoromethyl-4-pyridinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Isonicotinoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from moisture, heat, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.