Description

5-Fluoro-3,4-Dihydro-2H-Chromen-4-Amine is a high-value chromene derivative and a versatile synthetic building block. This compound is critical for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive chromene scaffold.
• Organic Synthesis Reagent: Serves as a precursor for creating more complex heterocyclic compounds and fluorinated molecules in academic and industrial R&D.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and biological target identification.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Fluoro-3,4-Dihydro-2H-Chromen-4-Amine
CAS No.	1018978-82-9
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	4-Amino-5-fluoro-3,4-dihydro-2H-chromene; 5-Fluoro-3,4-dihydro-2H-1-benzopyran-4-amine; 5-Fluoro-4-aminochroman; 4-Amino-5-fluorochroman; 1018978-82-9
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3,4-Dihydro-2H-Chromen-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.