Description

[2-(Difluoromethyl)Phenyl]Methanol, also known as 2-(Hydroxymethyl)Benzal Fluoride, is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a difluoromethyl and a benzylic alcohol group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Organic Electronics: Employed in the development of novel organic semiconductors and charge-transport materials due to its aromatic and fluorinated character.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with specific thermal or chemical resistance properties.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	[2-(Difluoromethyl)Phenyl]Methanol, 2-(Hydroxymethyl)Benzal Fluoride
CAS No.	1018678-49-3
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	2-(Difluoromethyl)benzyl alcohol; (2-(Difluoromethyl)phenyl)methanol; α-(Difluoromethyl)benzenemethanol; Benzenemethanol, 2-(difluoromethyl)-; 2-(Hydroxymethyl)benzal fluoride; 1-(Difluoromethyl)-2-(hydroxymethyl)benzene; 2-(Difluoromethyl)benzenemethanol
EINECS	Contact for details

Quality Control

Our [2-(Difluoromethyl)Phenyl]Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.