Description

1-(2-Fluorophenyl)Cyclopropane-1-Carbonyl Chloride is a high-purity, reactive organic intermediate featuring a cyclopropane ring and an acid chloride functional group. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research and development chemists and process scale-up teams for constructing novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, due to the fluorophenyl moiety's ability to modulate pharmacokinetic properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the cyclopropane scaffold contributes to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for asymmetric catalysis and organometallic chemistry applications.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	1-(2-Fluorophenyl)Cyclopropane-1-Carbonyl Chloride
CAS No.	1017391-66-0
Molecular Formula	C10H8ClFO
Molecular Weight	198.62 g/mol
Synonyms	2-Fluorophenyl cyclopropanecarbonyl chloride; 1-(2-Fluorophenyl)cyclopropanecarbonyl chloride; Cyclopropanecarbonyl chloride, 1-(2-fluorophenyl)-; 1-(2-Fluorophenyl)cyclopropanecarboxylic acid chloride; (2-Fluorophenyl)cyclopropanecarbonyl chloride; 1-(o-Fluorophenyl)cyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluorophenyl)Cyclopropane-1-Carbonyl Chloride adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.