Description

(3α,4α,8α,9β,13α,14β,16β,17Z)-16-(Acetyloxy)-3-Hydroxy-29-Nordammara-17(20),24-Dien-21-Oic Acid is a high-purity, semi-synthetic nordammarane diterpenoid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel bioactive molecules targeting various therapeutic pathways. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery programs. The compound's unique triterpenoid skeleton makes it a valuable scaffold for investigating anti-inflammatory, anticancer, and metabolic regulatory activities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthetic pathways for novel drug candidates, particularly in oncology and metabolic disease research.
• Reference Standard: Used as a high-purity analytical standard in Quality Control (QC) and Quality Assurance (QA) laboratories for method development and validation.
• Biochemical Research: Employed in academic and industrial R&D to study structure-activity relationships (SAR) of triterpenoid derivatives and their interaction with biological targets.
• Process Chemistry: Utilized in scale-up and optimization studies for the production of more complex nordammarane-based active pharmaceutical ingredients (APIs).
• Natural Product Synthesis: Acts as a precursor in the semi-synthesis of complex natural products and their analogs for biological screening.

Basic Information

Product Name	(3α,4α,8α,9β,13α,14β,16β,17Z)-16-(Acetyloxy)-3-Hydroxy-29-Nordammara-17(20),24-Dien-21-Oic Acid
CAS No.	1013937-16-0
Molecular Formula	C30H44O5
Molecular Weight	484.67 g/mol
Synonyms	29-Nor-dammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3-hydroxy-, (3α,4α,8α,9β,13α,14β,16β,17Z)-; 16β-Acetoxy-3α-hydroxy-29-nordammara-17(20),24-dien-21-oic acid; Nordammarane diterpenoid derivative; 29-Nordammara-17(20),24-dien-21-oic acid derivative; CAS 1013937-16-0; (17Z)-16-(Acetyloxy)-3-hydroxy-29-nordammara-17(20),24-dien-21-oic acid
EINECS	Contact for details

Quality Control

Our (3α,4α,8α,9β,13α,14β,16β,17Z)-16-(Acetyloxy)-3-Hydroxy-29-Nordammara-17(20),24-Dien-21-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR/MS for structural confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.