Description

1-(tert-Butyldimethylsilyloxy)-1-(Furan-2-Yl)-But-3-Ene is a specialized organosilicon-protected intermediate featuring a reactive butene chain and a furan heterocycle. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the controlled introduction of complex molecular fragments. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active molecules and functional polymers. The product, with CAS number 1012036-78-0, is supplied to meet the stringent demands of modern synthetic chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in constructing complex heterocyclic cores and side chains.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products.
• Material Science Research: Serves as a monomer or functional precursor in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The protected hydroxyl group and olefin moiety make it a suitable substrate for various palladium-catalyzed coupling reactions.
• Asymmetric Synthesis: Employed in the preparation of chiral intermediates for stereoselective synthesis pathways.
• Ligand and Catalyst Development: The furan ring can be utilized to create novel ligands for metal catalysis.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new synthetic routes in chemistry laboratories.

Basic Information

Item	Details
Product Name	1-(tert-Butyldimethylsilyloxy)-1-(Furan-2-Yl)-But-3-Ene
CAS No.	1012036-78-0
Molecular Formula	C14H24O2Si
Molecular Weight	252.43 g/mol
Synonyms	1-[(tert-Butyldimethylsilyl)oxy]-1-(2-furyl)-3-butene; 1-(TBDMSO)-1-(2-Furyl)-3-Butene; 1-(tert-Butyldimethylsilyloxy)-1-(2-furyl)but-3-ene; 1-(2-Furanyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-butene; TBS-protected furyl homoallylic alcohol; (1-(Furan-2-yl)-3-buten-1-yloxy)(tert-butyl)dimethylsilane
EINECS	Contact for details

Quality Control

Our 1-(tert-Butyldimethylsilyloxy)-1-(Furan-2-Yl)-But-3-Ene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.