Description

2-Bromo-1-(3-Fluoro-4-Nitrophenyl)Ethanone is a high-purity, specialized bromoketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromo and nitro substituents on a fluorinated aromatic ring, makes it a versatile precursor for constructing complex heterocyclic and pharmaceutical intermediates. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its reactive bromo and nitro groups.
• Material Science: Serves as a building block for synthesizing advanced organic materials, such as liquid crystals or photoactive polymers.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce the (3-fluoro-4-nitrophenyl) moiety.
• Heterocyclic Chemistry: A crucial starting material for the construction of various nitrogen- and oxygen-containing heterocycles, including benzofurans and indoles.

Basic Information

Product Name	2-Bromo-1-(3-Fluoro-4-Nitrophenyl)Ethanone
CAS No.	1010384-51-6
Molecular Formula	C8H5BrFNO3
Molecular Weight	262.03 g/mol
Synonyms	2-Bromo-1-(3-fluoro-4-nitrophenyl)ethan-1-one; 2-Bromo-3'-fluoro-4'-nitroacetophenone; α-Bromo-3-fluoro-4-nitroacetophenone; 3-Fluoro-4-nitro-α-bromoacetophenone; 1-(3-Fluoro-4-nitrophenyl)-2-bromoethanone; 2-Bromo-1-(3-fluoro-4-nitrophenyl)ethanone; Bromo(3-fluoro-4-nitrophenyl)methanone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(3-Fluoro-4-Nitrophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality ensures a reliable supply of this high-value intermediate for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and reactivity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.