Description

1-Ethyl-1H-Pyrazole-5-Carbonyl Chloride is a versatile and reactive organic intermediate, specifically an acyl chloride derivative of a pyrazole heterocycle. Its primary value lies in its role as a key building block for the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the life sciences sector who require a high-purity reagent for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing the pyrazole pharmacophore for various therapeutic targets.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides, where the pyrazole moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel pyrazole-based ligands for catalytic systems.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	1-Ethyl-1H-Pyrazole-5-Carbonyl Chloride
CAS No.	1006471-20-0
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	1-Ethyl-1H-pyrazole-5-carbonyl chloride; 1-Ethyl-5-pyrazolecarbonyl chloride; 1-Ethyl-1H-pyrazole-5-carboxylic acid chloride; 5-(Chlorocarbonyl)-1-ethyl-1H-pyrazole; 1-Ethylpyrazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Ethyl-1H-Pyrazole-5-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.