Description

1-Ethyl-1H-Pyrazole-3-Carbonyl Chloride is a versatile and reactive acid chloride derivative of a pyrazole heterocycle. This compound is a critical high-purity building block for the synthesis of more complex molecules, enabling the rapid introduction of a functionalized pyrazole moiety. It is primarily used by pharmaceutical, agrochemical, and advanced materials research organizations for drug discovery, crop protection agent development, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoactive materials for electronic applications.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.
• Bioconjugation and Probe Chemistry: The reactive carbonyl chloride group allows for efficient coupling to amines, useful in creating biochemical probes and labeled compounds.

Basic Information

Product Name	1-Ethyl-1H-Pyrazole-3-Carbonyl Chloride
CAS No.	1006471-16-4
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	1-Ethyl-1H-pyrazole-3-carbonyl chloride; 1-Ethyl-1H-pyrazole-3-carboxylic acid chloride; 3-Carboxy-1-ethylpyrazole chloride; 1-Ethylpyrazole-3-carbonyl chloride; 1-Ethyl-3-pyrazolecarbonyl chloride; 1-Ethyl-1H-3-pyrazolecarboxylic acid chloride; 3-(Chlorocarbonyl)-1-ethyl-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1-Ethyl-1H-Pyrazole-3-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications. We support cGMP and ISO 9001 compliant production for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Keep away from strong acids, bases, and moisture.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.