Description

4-Isothiocyanato-1-(3-Methyl-Benzyl)-1H-Pyrazole is a specialized heterocyclic organic compound featuring a reactive isothiocyanate functional group. This high-purity intermediate is critical for the synthesis of novel pharmacologically active molecules, particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new drug candidates, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new bioactive compounds.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new pesticides and herbicides.
• Chemical Biology Probes: Utilized to create isothiocyanate-conjugated probes for labeling and studying biological systems.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Isothiocyanato-1-(3-Methyl-Benzyl)-1H-Pyrazole
CAS No.	1004193-51-4
Molecular Formula	C12H11N3S
Molecular Weight	229.30 g/mol
Synonyms	1-[(3-Methylphenyl)methyl]-1H-pyrazole-4-isothiocyanate; 1-(3-Methylbenzyl)-1H-pyrazole-4-isothiocyanate; 4-Isothiocyanato-1-(3-methylbenzyl)pyrazole; 4-NCS-1-(3-Methylbenzyl)pyrazole; 4-Isothiocyanato-1-(3-methylbenzyl)-1H-pyrazole; 1-(3-Methylbenzyl)-4-isothiocyanatopyrazole
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanato-1-(3-Methyl-Benzyl)-1H-Pyrazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to meet the stringent requirements of our pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.