Description

1-(3,4-Dichloro-Benzyl)-4-Isothiocyanato-1H-Pyrazole is a specialized heterocyclic organic compound featuring a pyrazole core functionalized with an isothiocyanate group and a dichlorobenzyl substituent. This unique molecular architecture makes it a critical building block and intermediate in advanced chemical synthesis, particularly for the development of novel active ingredients. It is primarily needed by pharmaceutical research organizations and agrochemical companies engaged in the discovery and development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Research: Used as a building block for developing new generation pesticides, herbicides, and fungicides with specific modes of action.
• Chemical Biology Probe: The reactive isothiocyanate group allows for covalent modification of proteins, making it useful in proteomics and target identification studies.
• Material Science Research: Potential intermediate for creating specialized polymers or functional materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-(3,4-Dichloro-Benzyl)-4-Isothiocyanato-1H-Pyrazole
CAS No.	1004193-36-5
Molecular Formula	C11H7Cl2N3S
Molecular Weight	284.16 g/mol
Synonyms	4-Isothiocyanato-1-[(3,4-dichlorophenyl)methyl]-1H-pyrazole; 1-[(3,4-Dichlorophenyl)methyl]-1H-pyrazole-4-isothiocyanate; 1-(3,4-Dichlorobenzyl)-1H-pyrazole-4-isothiocyanate; 1-(3,4-Dichlorobenzyl)-4-isothiocyanatopyrazole; 4-Isothiocyanato-1-(3,4-dichlorobenzyl)pyrazole; Pyrazole-4-isothiocyanate, 1-(3,4-dichlorobenzyl)-; 1004193-36-5
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dichloro-Benzyl)-4-Isothiocyanato-1H-Pyrazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.