Description

3-Acetylamino-2-Fluorobenzyl Alcohol is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and benzyl alcohol moiety are crucial for modulating biological activity and physicochemical properties. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors engaged in the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine substituent enhances efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel fluorinated polymers and liquid crystals with unique optical and electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags for biochemical and diagnostic applications.

Basic Information

Product Name	3-Acetylamino-2-Fluorobenzyl Alcohol
CAS No.	1003707-72-9
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	N-[2-Fluoro-3-(hydroxymethyl)phenyl]acetamide; 2-Fluoro-3-(acetamidomethyl)benzyl alcohol; 1-(2-Fluoro-3-(hydroxymethyl)phenyl)ethan-1-one; 3-Acetamido-2-fluorobenzyl alcohol; 2-Fluoro-3-(hydroxymethyl)acetanilide; (2-Fluoro-3-(hydroxymethyl)phenyl)acetamide
EINECS	Contact for details

Quality Control

Our 3-Acetylamino-2-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the high-purity standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.