Description

4-Isothiocyanato-1,5-Dimethyl-1H-Pyrazole is a specialized heterocyclic building block featuring a reactive isothiocyanate functional group. This compound is of significant value in synthetic organic and medicinal chemistry for the construction of novel molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for creating thiourea and heterocyclic derivatives with potential biological activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the pyrazole-isothiocyanate scaffold can confer specific modes of action.
• Chemical Biology Probe Synthesis: Employed to create affinity probes or labeling reagents for studying protein interactions and enzymatic activity due to its reactive isothiocyanate group.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.
• Organic Synthesis Building Block: Provides a versatile handle for [3+2] cycloadditions and nucleophilic addition reactions to construct complex nitrogen-containing heterocycles.

Basic Information

Product Name	4-Isothiocyanato-1,5-Dimethyl-1H-Pyrazole
CAS No.	1001500-56-6
Molecular Formula	C6H7N3S
Molecular Weight	153.21 g/mol
Synonyms	1,5-Dimethyl-4-isothiocyanato-1H-pyrazole; 1H-Pyrazole, 4-isothiocyanato-1,5-dimethyl-; 4-Isothiocyanato-1,5-dimethylpyrazole; 1,5-Dimethyl-1H-pyrazole-4-isothiocyanate
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanato-1,5-Dimethyl-1H-Pyrazole is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and degradation. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.