Description

2-Chloro-n-[(3-Iodophenyl)Methyl]-2',3'-o-(1-Methylethylidene) Adenosine is a chemically modified nucleoside analog, a key intermediate in advanced pharmaceutical research and development. This compound is specifically engineered for high-value applications in medicinal chemistry, offering a versatile scaffold for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of targeted small-molecule drugs, particularly in areas such as oncology and metabolic disorders.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel adenosine receptor-targeting drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Probe Development: Serves as a precursor for labeled compounds used in enzyme inhibition assays and cellular signaling pathway studies.
• Preclinical Drug Development: Employed in the synthesis of compounds for pharmacokinetic, pharmacodynamic, and toxicology evaluations.
• Academic Research: Utilized in university and institutional labs for fundamental research on nucleoside chemistry and receptor biology.

Basic Information

Product Name	2-Chloro-n-[(3-Iodophenyl)Methyl]-2',3'-o-(1-Methylethylidene) Adenosine
CAS No.	1000980-71-1
Molecular Formula	C21H22ClIN6O4
Molecular Weight	584.79 g/mol
Synonyms	2-Chloro-N-[(3-iodophenyl)methyl]-2',3'-O-(1-methylethylidene)adenosine; 2-Chloroadenosine derivative, 2',3'-O-isopropylidene-2-chloro-N-[(3-iodobenzyl)]adenosine; 2-Cl-N6-[(3-Iodobenzyl)]-2',3'-O-isopropylideneadenosine; 1000980-71-1; Adenosine, 2-chloro-N-[(3-iodophenyl)methyl]-2',3'-O-(1-methylethylidene)-; Research Grade 2-Chloro Modified Adenosine
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-[(3-Iodophenyl)Methyl]-2',3'-o-(1-Methylethylidene) Adenosine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as HPLC, NMR, and mass spectrometry. We support compliance with cGMP and ISO 9001 standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.