Description

4-Bromo-3,5-Difluorophenylisothiocyanate is a specialized aromatic isothiocyanate derivative, a key building block in advanced organic synthesis. Its value lies in its dual functionality, where the reactive isothiocyanate group enables efficient conjugation, and the halogenated difluorophenyl ring provides unique electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients, creating heterocyclic compounds, and synthesizing functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor for synthesizing novel drug candidates, especially in kinase inhibitor and targeted therapy research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Ligand and Probe Development: Serves as a versatile scaffold for creating chemical probes, bio-conjugates, and fluorescent markers for biological imaging and diagnostics.
• Material Science: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Chemical Biology: Facilitates the study of protein interactions and enzyme activity through isothiocyanate-mediated labeling and cross-linking.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-Bromo-3,5-Difluorophenylisothiocyanate
CAS No.	1000577-92-3
Molecular Formula	C7H2BrF2NS
Molecular Weight	250.07 g/mol
Synonyms	1-Bromo-3,5-difluoro-4-isothiocyanatobenzene; 3,5-Difluoro-4-bromophenyl isothiocyanate; 4-Bromo-3,5-difluorobenzene isothiocyanate; Isothiocyanic acid, 4-bromo-3,5-difluorophenyl ester; 4-Bromo-3,5-difluorophenyl mustard oil; (4-Bromo-3,5-difluorophenyl)isothiocyanate
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3,5-Difluorophenylisothiocyanate is produced and tested under strict quality management systems to ensure consistency and purity for research and development. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development from milligram to kilogram scale with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.