Description

4-Fluoro-2-Nitrophenylisothiocyanate is a specialized aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the isothiocyanate group, which readily forms thiourea linkages, making it indispensable for constructing complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in creating novel herbicides, fungicides, or pesticides by incorporating the fluoronitrophenyl moiety into active molecules.
• Peptide & Protein Modification: Acts as a coupling agent or labeling reagent for modifying amino groups in peptides, proteins, or other biomolecules to study function or create conjugates.
• Material Science: Building block for synthesizing advanced polymers, liquid crystals, or organic semiconductors where the electron-withdrawing nitro and fluoro groups tune electronic properties.
• Chemical Biology Probes: Utilized in developing activity-based probes (ABPs) or affinity labels to study biological processes and identify drug targets.
• Dye & Pigment Synthesis: Intermediate in the production of specialized dyes and pigments requiring the specific chromophoric and substituent effects of this structure.

Basic Information

Product Name	4-Fluoro-2-Nitrophenylisothiocyanate
CAS No.	1000576-88-4
Molecular Formula	C7H3FN2O2S
Molecular Weight	198.17 g/mol
Synonyms	1-Fluoro-4-isothiocyanato-3-nitrobenzene; 2-Nitro-4-fluorophenyl isothiocyanate; 4-Fluoro-2-nitrobenzenisothiocyanate; 4-Fluoro-2-nitro-phenylisothiocyanate; (4-Fluoro-2-nitrophenyl)isothiocyanate; Isothiocyanic acid 4-fluoro-2-nitrophenyl ester; 3-Nitro-4-fluorophenyl isothiocyanate
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Nitrophenylisothiocyanate is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure to light during handling and storage.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.