Description

4-Bromo-3-Fluoro-2-Methylphenylisothiocyanate is a specialized aromatic isothiocyanate derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique halogenated and thiocyanate-functionalized structure enables precise molecular modifications. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, crop protection, and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced functional materials.
• Chemical Biology Probes: Utilized to create isothiocyanate-based affinity probes for protein labeling and activity-based profiling studies.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing complex ligands used in catalytic systems and coordination chemistry.

Basic Information

Product Name	4-Bromo-3-Fluoro-2-Methylphenylisothiocyanate
CAS No.	1000576-39-5
Molecular Formula	C8H5BrFNS
Molecular Weight	246.10 g/mol
Synonyms	1-Bromo-2-fluoro-6-isothiocyanato-3-methylbenzene; 2-Methyl-4-bromo-3-fluorophenyl isothiocyanate; 4-Bromo-3-fluoro-o-tolyl isothiocyanate; 3-Fluoro-4-bromo-2-methylphenyl isothiocyanate; Isothiocyanic acid, 4-bromo-3-fluoro-2-methylphenyl ester; (4-Bromo-3-fluoro-2-methylphenyl) isothiocyanate
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoro-2-Methylphenylisothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.