Description

2-Bromo-6-Fluoro-4-Methylphenylisothiocyanate is a versatile and highly reactive organic building block characterized by its isothiocyanate functional group. This compound is essential for the synthesis of complex molecules, particularly in pharmaceutical research and agrochemical development, where it serves as a key precursor for introducing specific heterocyclic and thiourea moieties. It is primarily sought after by research chemists and process development scientists in the life sciences and specialty chemical sectors for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by constructing bioactive heterocyclic scaffolds.
• Chemical Biology Probe Synthesis: The reactive isothiocyanate group allows for site-specific conjugation with amines, making it valuable for creating fluorescent tags, affinity labels, and other molecular probes.
• Material Science: Employed in the development of advanced polymers and functional materials with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Bromo-6-Fluoro-4-Methylphenylisothiocyanate
CAS No.	1000576-04-4
Molecular Formula	C8H5BrFNS
Molecular Weight	246.10 g/mol
Synonyms	2-Bromo-6-fluoro-4-methylphenyl isothiocyanate; 1-Bromo-3-fluoro-5-isothiocyanato-2-methylbenzene; 4-Methyl-2-bromo-6-fluorophenyl isothiocyanate; (2-Bromo-6-fluoro-4-methylphenyl)isothiocyanate; 2-Bromo-6-fluoro-p-tolyl isothiocyanate; Isothiocyanic acid, 2-bromo-6-fluoro-4-methylphenyl ester
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoro-4-Methylphenylisothiocyanate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.