Description

4-Fluoro-3-Methoxyphenylisothiocyanate is a versatile aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive isothiocyanate group, which readily undergoes addition and cyclization reactions to form heterocyclic cores and functionalized intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced activity.
• Heterocyclic Chemistry: Used in the construction of thiourea derivatives, thiazoles, and other nitrogen-sulfur containing heterocycles important in medicinal chemistry.
• Chemical Biology Probes: Employed in the development of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Material Science Research: Monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library production.

Basic Information

Product Name	4-Fluoro-3-Methoxyphenylisothiocyanate
CAS No.	1000575-99-4
Molecular Formula	C8H6FNO2S
Molecular Weight	199.20 g/mol
Synonyms	1-Fluoro-2-Methoxy-4-Isothiocyanatobenzene; 4-Fluoro-3-Methoxybenzenisothiocyanate; 3-Methoxy-4-fluorophenyl isothiocyanate; 4-Fluoro-3-methoxyphenyl isothiocyanate; (4-Fluoro-3-methoxyphenyl)isothiocyanate; 4-Fluoro-3-methoxy phenylisothiocyanate; 4-Fluoro-3-methoxy-1-isothiocyanatobenzene
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methoxyphenylisothiocyanate is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet the exacting standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.