Description

4-Bromo-2,6-Difluorophenylisothiocyanate is a versatile and highly reactive aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of bromine and fluorine substituents, which allow for selective functionalization and tuning of electronic properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Ligand and Material Science: Serves as a building block for creating specialized ligands for catalysis and functional materials with tailored properties.
• Chemical Biology Probe Development: The reactive isothiocyanate group enables conjugation to biomolecules for labeling and studying biological pathways.
• Heterocyclic Chemistry: Fundamental starting material for constructing complex sulfur- and nitrogen-containing heterocycles like benzothiazoles and thioureas.
• Custom Synthesis and R&D: Employed in contract research and custom manufacturing for specialized chemical projects requiring halogenated aromatic intermediates.

Basic Information

Item	Details
Product Name	4-Bromo-2,6-Difluorophenylisothiocyanate
CAS No.	1000574-64-0
Molecular Formula	C7H2BrF2NS
Molecular Weight	250.07 g/mol
Synonyms	4-Bromo-2,6-difluorophenyl isothiocyanate; 2,6-Difluoro-4-bromophenyl isothiocyanate; 1-Bromo-3,5-difluoro-4-isothiocyanatobenzene; Isothiocyanic acid, 4-bromo-2,6-difluorophenyl ester; 4-Bromo-2,6-difluorobenzene isothiocyanate; (4-Bromo-2,6-difluorophenyl)isothiocyanate
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,6-Difluorophenylisothiocyanate is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.