Description

4-Bromo-2,3-Difluorophenylisothiocyanate is a specialized aromatic isothiocyanate derivative, distinguished by its bromo and difluoro substituents. This compound serves as a critical high-purity building block for the synthesis of complex molecules, offering precise reactivity for constructing heterocyclic scaffolds and functional materials. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories engaged in the development of novel active ingredients and advanced chemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with enhanced activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and target engagement.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	4-Bromo-2,3-Difluorophenylisothiocyanate
CAS No.	1000574-53-7
Molecular Formula	C7H2BrF2NS
Molecular Weight	250.07 g/mol
Synonyms	2,3-Difluoro-4-bromophenyl isothiocyanate; 4-Bromo-2,3-difluorophenyl isothiocyanate; 1-Bromo-2,3-difluoro-4-isothiocyanatobenzene; Isothiocyanic acid, 4-bromo-2,3-difluorophenyl ester; (4-Bromo-2,3-difluorophenyl) isothiocyanate
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2,3-Difluorophenylisothiocyanate adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.