Description

4-Bromo-2,3-Dichlorophenylisothiocyanate is a versatile and highly functionalized aromatic isothiocyanate building block. This compound is critical for the synthesis of complex heterocyclic systems and advanced pharmaceutical intermediates. It is primarily utilized by research chemists and process development scientists in the agrochemical and pharmaceutical industries for lead optimization and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for creating thiourea and heterocyclic scaffolds with biological activity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure for bioactivity.
• Chemical Biology Probe: The reactive isothiocyanate group allows for selective labeling and modification of proteins and other biomolecules in research applications.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers and advanced organic materials.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions and nucleophilic aromatic substitution to construct complex molecular architectures.

Basic Information

Product Name	4-Bromo-2,3-Dichlorophenylisothiocyanate
CAS No.	1000574-11-7
Molecular Formula	C7H2BrCl2NS
Molecular Weight	307.37 g/mol
Synonyms	1-Bromo-2,3-dichloro-4-isothiocyanatobenzene; 2,3-Dichloro-4-bromophenyl isothiocyanate; 4-Bromo-2,3-dichlorobenzene isothiocyanate; Isothiocyanic acid, 4-bromo-2,3-dichlorophenyl ester; (4-Bromo-2,3-dichlorophenyl)isothiocyanate
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3-Dichlorophenylisothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our analytical methods, including HPLC, NMR, and IR, are validated to provide reliable specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.