Description

2-Fluoro-3-Methylbenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2-fluoro-3-methylbenzoyl moiety into target molecules, enabling the creation of complex structures with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise functionalization for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-inflammatory agents, and oncology treatments.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity, stability, and metabolic resistance.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modifier: Employed to introduce fluorinated benzoyl groups into polymer chains, modifying thermal stability, chemical resistance, and surface properties of high-performance materials.
• Custom Synthesis & Contract Manufacturing: A crucial reagent for custom chemical synthesis (CDMO) services catering to R&D and pilot-scale production needs.
• Chemical Research & Development: Fundamental reagent in academic and industrial R&D labs for exploring new fluorination chemistry, coupling reactions, and heterocyclic compound synthesis.

Basic Information

Product Name	2-Fluoro-3-Methylbenzoyl Chloride
CAS No.	1000339-85-4
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-Fluoro-3-methylbenzoyl chloride; 3-Methyl-2-fluorobenzoyl chloride; 2-Fluoro-m-toluoyl chloride; o-Fluoro-m-toluoyl chloride; 2-Fluoro-3-methylbenzoic acid chloride; 1000339-85-4; Benzoyl chloride, 2-fluoro-3-methyl-
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Methylbenzoyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support applications requiring high-purity intermediates, including those under cGMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from moisture, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.