Description

7-Cyano-7-Deaza-2'-Deoxy Guanosine is a high-purity, modified nucleoside analog of significant interest in advanced pharmaceutical and diagnostic research. This compound serves as a critical building block for the synthesis of oligonucleotides with enhanced properties, such as improved stability and binding affinity. It is primarily utilized by research institutions and biotech companies engaged in the development of novel therapeutics, molecular probes, and diagnostic assays.

Application

• Oligonucleotide Synthesis: A key monomer for constructing modified DNA strands in antisense, siRNA, and aptamer research.
• Pharmaceutical Intermediates: Serves as a vital precursor in the development of nucleoside-based antiviral and anticancer drug candidates.
• Molecular Biology Research: Used in the study of nucleic acid structure, function, and enzyme interactions.
• Diagnostic Probe Development: Incorporated into fluorescent or labeled probes for high-sensitivity detection systems.
• Bioconjugation: The cyano group offers a handle for further chemical modification and conjugation to other molecules or surfaces.

Basic Information

Item	Detail
Product Name	7-Cyano-7-Deaza-2'-Deoxy Guanosine
CAS No.	199859-58-0
Molecular Formula	C11H11N5O4
Molecular Weight	277.24 g/mol
Synonyms	7-Cyano-7-deaza-2'-deoxyguanosine; 7-CN-7-deaza-dG; 2'-Deoxy-7-cyano-7-deazaguanosine; 7-Cyano-7-deazaguanosine 2'-deoxyriboside; c7dG(CN); Pyrrolo[2,3-d]pyrimidine nucleoside analog; 7-CN-7-deaza-2'-deoxy-Guanosine
EINECS	Contact for details

Quality Control

Our 7-Cyano-7-Deaza-2'-Deoxy Guanosine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.