Description

Revaprazan is a selective potassium-competitive acid blocker (P-CAB) used as an active pharmaceutical ingredient (API). This compound is significant for its potent and long-lasting inhibition of gastric acid secretion, offering a therapeutic mechanism for managing acid-related disorders. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of gastrointestinal therapeutics and novel drug formulations.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of anti-ulcer medications.
• Key intermediate in advanced pharmaceutical research for new gastroprotective agents.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical research tool for studying H+/K+ ATPase (proton pump) inhibition mechanisms.
• Pre-clinical and clinical research material for investigating treatments for gastroesophageal reflux disease (GERD).
• Development of combination therapies for Helicobacter pylori eradication.

Basic Information

Product Name	Revaprazan
CAS No.	199463-33-7
Molecular Formula	C₂₆H₂₈N₄O₂
Molecular Weight	428.53 g/mol
Synonyms	Revaprazan; RQ-00000007; YH1885; 5,6-Dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1H-benzimidazol-2-yl)pyrimidine; 2-[[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)-2-pyrimidinyl]amino]-5-fluorobenzonitrile; 5-Fluoro-2-[[4-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyrimidinyl]amino]benzonitrile
EINECS	Contact for details

Quality Control

Our Revaprazan is manufactured under strict quality management systems, with purity typically meeting or exceeding 98.0% (by HPLC). Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure compliance with ICH guidelines and customer-specific requirements. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% min.
Related Substances (HPLC)	Total impurities: 2.0% max. Any individual impurity: 0.5% max.
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	1.0% max.
Heavy Metals	20 ppm max.

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.