Description

[1-(4-Fluoro-Phenyl)-Cyclopropyl]-Methanol is a versatile fluorinated cyclopropane derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring a fluorinated aromatic ring fused to a strained cyclopropane ring bearing a hydroxymethyl group, makes it invaluable for constructing complex molecular architectures with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for synthesizing fluorinated polymers and liquid crystals with unique electronic and optical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, specialized fluorinated intermediates.

Basic Information

Product Name	[1-(4-Fluoro-Phenyl)-Cyclopropyl]-Methanol
CAS No.	198976-40-8
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	(1-(4-Fluorophenyl)cyclopropyl)methanol; 1-(4-Fluorophenyl)cyclopropanemethanol; 4-Fluoro-α-(hydroxymethyl)benzenecacetonitrile, cyclopropane deriv.; (1-(p-Fluorophenyl)cyclopropyl)methanol; p-Fluoro-α-(hydroxymethyl)benzenecacetonitrile cyclopropane derivative
EINECS	Contact for details

Quality Control

Our [1-(4-Fluoro-Phenyl)-Cyclopropyl]-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.