Description

Pneumocandin CAS NO 198706-35-3 is a semi-synthetic lipopeptide antifungal agent belonging to the echinocandin class. This compound is a critical intermediate in the synthesis of advanced antifungal pharmaceuticals, valued for its potent activity against fungal cell wall synthesis. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of next-generation antifungal treatments for systemic infections.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced echinocandin-based antifungal drugs like caspofungin.
• Antifungal Drug Development: Used in R&D for creating novel antifungal agents targeting invasive fungal infections such as candidiasis and aspergillosis.
• Biochemical Research: Serves as a reference standard and tool compound in pharmacological studies to investigate the mechanism of action of glucan synthase inhibitors.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the controlled production of antifungal APIs under current Good Manufacturing Practice (cGMP) standards.
• Microbiology & Mycology Studies: Utilized in laboratory settings to study fungal resistance patterns and the efficacy of echinocandin derivatives.

Basic Information

Product Name	Pneumocandin
CAS No.	198706-35-3
Molecular Formula	C52H81N7O17
Molecular Weight	1052.2 g/mol
Synonyms	Pneumocandin B0; (4R,5R)-4,5-Dihydroxy-N2-[(1S,2S)-1-hydroxy-2-hydroxy-1-(4-hydroxy-3-(sulfooxy)phenyl)propan-2-yl]-L-ornithyl-1-[(1S,2S)-1-methyl-2-[(1-oxooctyl)amino]butyl]-4-[(4R)-4-hydroxy-L-prolyl]-L-threonyl-2-piperidinecarboxamide; L-Threonine, N-[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-11-[(1R)-1-hydroxyethyl]-21-(4-hydroxy-3-sulfooxybenzyl)-6-[(1S)-1-methyl-2-[(1-oxooctyl)amino]butyl]-20,26-dihydroxy-3,15-bis(1-methylethyl)-1,4,10,12,14,16,22,25-octaoxo-9-(phenylmethyl)-2,17-dioxa-5,8,11,14,23,26-hexaazatricyclo[20.4.0.07,12]hexacosan-24-yl]-; Caspofungin Intermediate; Echinocandin B0
EINECS	Contact for details

Quality Control

Our Pneumocandin is manufactured under strict quality systems to ensure it meets the exacting standards required for pharmaceutical synthesis. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific pharmacopeial (e.g., USP) or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.