Description

1,3-Cyclopentanedicarboxylic Acid Difluoride, cis- (9Ci) is a high-purity, reactive fluorinated building block essential for advanced organic synthesis. This compound is valued for its ability to introduce the cyclopentane dicarbonyl moiety under mild conditions, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and advanced organic electronic materials.
• Peptide Mimetics: Employed in medicinal chemistry to create conformationally restricted peptide analogs and macrocycles.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in metal-catalyzed reactions to form carbon-carbon bonds.
• Fluorine Chemistry: A valuable reagent for introducing fluorinated segments into target molecules to modulate physicochemical properties.

Basic Information

Product Name	1,3-Cyclopentanedicarboxylic Acid Difluoride, cis- (9Ci)
CAS No.	198079-07-1
Molecular Formula	C7H6F2O2
Molecular Weight	160.12 g/mol
Synonyms	cis-1,3-Cyclopentanedicarboxylic Acid Difluoride; cis-1,3-Cyclopentanedicarbonyl Difluoride; 1,3-Cyclopentanedicarboxylic Acid, 1,3-Difluoride, cis-; Cyclopentane-1,3-dicarboxylic Acid Difluoride (cis-); 198079-07-1; cis-Cyclopentane-1,3-dicarbonyl Difluoride
EINECS	Contact for details

Quality Control

Our 1,3-Cyclopentanedicarboxylic Acid Difluoride, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.