Description

Apricoxib is a potent and selective cyclooxygenase-2 (COX-2) inhibitor, a class of compounds known for their anti-inflammatory and analgesic properties. This high-purity active pharmaceutical ingredient (API) is critical for research and development in advanced therapeutic areas, offering a targeted mechanism of action. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract manufacturing organizations (CMOs) focused on developing novel non-steroidal anti-inflammatory drugs (NSAIDs) and exploring oncology applications.

Application

• Pharmaceutical R&D: Primary use as a reference standard and active ingredient in the development of next-generation COX-2 inhibitor drugs.
• Preclinical Research: Investigation of anti-inflammatory, analgesic, and potential anti-cancer mechanisms in various in vitro and in vivo models.
• Biochemical Assay Development: Used as a selective inhibitor to study COX-2 enzyme activity and pathway signaling in biochemical and pharmacological studies.
• Academic Research: Serves as a key tool compound for university and institutional research into inflammation, pain, and related disease pathways.
• Formulation Studies: Employed in the development and optimization of drug delivery systems, such as tablets or injectables, for enhanced bioavailability.

Basic Information

Product Name	Apricoxib
CAS No.	197904-84-0
Molecular Formula	C17H14F3N3O2S
Molecular Weight	381.37 g/mol
Synonyms	Apricoxib; TG01; CS-706; 2-(4-Ethoxyphenyl)-4-methyl-1-(4-sulfamoylphenyl)-1H-pyrrole-3-carboxylic acid; 4-[2-(4-Ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzenesulfonamide; UNII-0V5F5B0B6U; COX-2 Inhibitor TG01
EINECS	Contact for details

Quality Control

Our Apricoxib is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and control of specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.