Description

L 778,123 is a high-purity, synthetic organic compound used as a key intermediate in advanced pharmaceutical research and development. Its primary value lies in enabling the synthesis of complex molecules for targeted therapeutic applications, offering researchers a reliable and well-characterized building block. This product is essential for R&D laboratories and pharmaceutical manufacturers focused on oncology, neurology, and other life science sectors requiring precise chemical tools.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors, particularly relevant for antiviral and anticancer drug discovery programs.
• Chemical Biology Probes: Serves as a core structure for creating specialized probes to study enzyme function and cellular pathways.
• Medicinal Chemistry: Employed by medicinal chemists for structure-activity relationship (SAR) studies and lead optimization processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the biopharma industry.

Basic Information

Product Name	L 778,123
CAS No.	197853-31-9
Molecular Formula	C27H30N4O4S
Molecular Weight	506.62 g/mol
Synonyms	L-778,123; L778123; (2S)-N-[(2S)-1-[[(2S,3S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[(2-Acetamidoacetamido)acetamido]-3-phenylpropanamido]-4-methyl-1-oxopentan-2-yl]carbamoyl]azetidin-3-yl]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[(2S)-2-(methoxycarbonylamino)-3-phenylpropanamido]acetamide; Merck L 778123 Protease Inhibitor
EINECS	Contact for details

Quality Control

Every batch of L 778,123 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.