Description

2-Amino-4-Fluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its bifunctional structure, featuring both an amino and a benzyl alcohol group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe and Dye Chemistry: Employed in the synthesis of fluorophores and molecular probes for bioimaging and diagnostic applications.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and specialty materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Item	Details
Product Name	2-Amino-4-Fluorobenzyl Alcohol
CAS No.	197783-88-3
Molecular Formula	C7H8FNO
Molecular Weight	141.14 g/mol
Synonyms	4-Fluoro-2-aminobenzyl alcohol; (2-Amino-4-fluorophenyl)methanol; 2-Amino-4-fluorobenzenemethanol; 4-Fluoroanthranilyl alcohol; 2-(Hydroxymethyl)-5-fluoroaniline; 5-Fluoro-2-aminobenzyl alcohol; Benzenemethanol, 2-amino-4-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-Fluorobenzyl Alcohol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.