Description

Benzenemethanol, α-(Difluoromethyl)-2-Nitro- (9Ci) is a specialized fluorinated nitrobenzyl alcohol derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both difluoromethyl and nitro substituents, makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used to develop novel herbicides and pesticides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Material Science: Building block for advanced polymers and liquid crystals, leveraging its aromatic and fluorinated characteristics.
• Organic Synthesis: Versatile reagent for introducing the difluoromethylnitrobenzyl moiety into complex molecular architectures via nucleophilic substitution or reduction reactions.
• Chemical Biology: Potential use in designing activity-based probes and molecular tags due to its reactive functional groups.

Basic Information

Product Name	Benzenemethanol, α-(Difluoromethyl)-2-Nitro- (9Ci)
CAS No.	197783-86-1
Molecular Formula	C8H7F2NO3
Molecular Weight	203.15 g/mol
Synonyms	2-Nitro-α-(difluoromethyl)benzenemethanol; α-(Difluoromethyl)-2-nitrobenzenemethanol; 1-(Difluoromethyl)-1-(2-nitrophenyl)methanol; (2-Nitrophenyl)(difluoromethyl)methanol; 2-Nitrobenzyl Alcohol, α,α-Difluoro-; NSC 405124; (Difluoromethyl)(2-nitrophenyl)methanol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, α-(Difluoromethyl)-2-Nitro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.