Description

2,5-Dimethyl-1,3-oxazole-4-carbonyl chloride is a highly reactive acyl chloride derivative of a substituted oxazole, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2,5-dimethyloxazole-4-carbonyl moiety, a privileged scaffold found in various bioactive molecules and functional materials. This intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and performance compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing heterocyclic amides or hydrazides.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that incorporate the oxazole ring system.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, photoactive materials, or polymers with specific electronic properties.
• Peptide Mimetics and Bioconjugation: Useful for modifying peptides or creating stable conjugates due to its high reactivity with amines.
• Custom Chemical Synthesis: A versatile reagent for contract research organizations (CROs) and CDMOs serving the life sciences sector.

Basic Information

Product Name	2,5-Dimethyl-1,3-oxazole-4-carbonyl chloride
CAS No.	197719-27-0
Molecular Formula	C7H8ClNO2
Molecular Weight	173.60 g/mol
Synonyms	4-Chlorocarbonyl-2,5-dimethyloxazole; 2,5-Dimethyl-4-oxazolecarbonyl chloride; 2,5-Dimethyloxazole-4-carbonyl chloride; 2,5-Dimethyl-1,3-oxazole-4-carboxylic acid chloride; 4-Carboxy-2,5-dimethyloxazole chloride; 197719-27-0; Oxazole-4-carbonyl chloride, 2,5-dimethyl-
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dimethyl-1,3-oxazole-4-carbonyl chloride is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced pharmaceutical intermediates, ensuring traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its nature as a moisture-sensitive and reactive acid chloride, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) and protected from humidity. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.