Description

4-(Pentafluorosulfanyl)Benzoyl Chloride is a high-value, reactive organofluorine building block characterized by the unique pentafluorosulfanyl (SF5) functional group. This compound is critical for introducing the highly electronegative, lipophilic, and thermally stable SF5 moiety into target molecules, significantly altering their physical and biological properties. It is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active ingredients, and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS, metabolic, and anti-inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the SF5 group enhances bioactivity and environmental stability.
• Liquid Crystal & Advanced Material Precursor: Serves as a monomer or precursor for creating specialty polymers, liquid crystals, and electronic materials with unique dielectric properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for constructing complex fluorinated aromatic systems and exploring new reaction pathways.
• Dye & Pigment Chemistry: Acts as an intermediate for synthesizing high-performance, light-fast fluorinated dyes and pigments.

Basic Information

Product Name	4-(Pentafluorosulfanyl)Benzoyl Chloride
CAS No.	197384-98-8
Molecular Formula	C7H2ClF5OS
Molecular Weight	264.60 g/mol
Synonyms	p-(Pentafluorosulfanyl)benzoyl chloride; 4-SF5-Benzoyl chloride; Benzoyl chloride, 4-(pentafluoro-λ6-sulfanyl)-; 4-(SF5)C6H4COCl; α-Chloro-4-(pentafluorosulfanyl)toluene; 4-(Pentafluorosulfuranyl)benzoyl chloride; (4-SF5-Phenyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-(Pentafluorosulfanyl)Benzoyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results for assay, identity, and impurity profiles (typically by GC, HPLC, and NMR), is supplied with each shipment to guarantee consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.